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Secreted parasite Pin1 isomerase stabilizes host PKM2 to reprogram host cell metabolism
Metabolic reprogramming is an important feature of host–pathogen interactions and a hallmark of tumorigenesis. The intracellular apicomplexa parasite Theileria induces a Warburg-like effect in host leukocytes by hijacking signaling machineries, epigenetic regulators and transcriptional programs to c...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491484/ https://www.ncbi.nlm.nih.gov/pubmed/31044177 http://dx.doi.org/10.1038/s42003-019-0386-6 |