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Age-dependent changes in clock neuron structural plasticity and excitability are associated with a decrease in circadian output behavior and sleep

Aging has significant effects on circadian behavior across a wide variety of species, but the underlying mechanisms are poorly understood. Previous work has demonstrated the age-dependent decline in behavioral output in the model organism Drosophila. We demonstrate that this age-dependent decline in...

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Detalles Bibliográficos
Autores principales: Curran, Jack A., Buhl, Edgar, Tsaneva-Atanasova, Krasimira, Hodge, James J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491500/
https://www.ncbi.nlm.nih.gov/pubmed/30825692
http://dx.doi.org/10.1016/j.neurobiolaging.2019.01.025