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Lipidomic Alterations in the Mitochondria of Aged Parkin Null Mice Relevant to Autophagy

Mitochondrial quality control is important in neurological diseases, but in genetic Parkinson’s disease caused by mutations in PINK and parkin mitochondrial degradation through autophagy is crucial. Reductions in autophagy and mitophagy are implicated in aging, age related diseases and Parkinson. Th...

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Detalles Bibliográficos
Autores principales: Gaudioso, Angel, Garcia-Rozas, Patricia, Casarejos, Maria Jose, Pastor, Oscar, Rodriguez-Navarro, Jose Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491511/
https://www.ncbi.nlm.nih.gov/pubmed/31068772
http://dx.doi.org/10.3389/fnins.2019.00329