Evaluating and Correcting Inherent Bias of microRNA Expression in Illumina Sequencing Analysis

microRNA (miRNA) expression profiles based on the highly powerful Illumina sequencing technology rely on the construction of cDNA libraries in which adaptor ligation is known to deeply favor some miRNAs over others. This introduces erroneous measurements of the miRNA abundances and relative miRNA qu...

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Detalles Bibliográficos
Autores principales: Baroin-Tourancheau, Anne, Jaszczyszyn, Yan, Benigni, Xavier, Amar, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491513/
https://www.ncbi.nlm.nih.gov/pubmed/31069233
http://dx.doi.org/10.3389/fmolb.2019.00017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491513/
https://www.ncbi.nlm.nih.gov/pubmed/31069233
http://dx.doi.org/10.3389/fmolb.2019.00017

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