Cargando…
Evaluating and Correcting Inherent Bias of microRNA Expression in Illumina Sequencing Analysis
microRNA (miRNA) expression profiles based on the highly powerful Illumina sequencing technology rely on the construction of cDNA libraries in which adaptor ligation is known to deeply favor some miRNAs over others. This introduces erroneous measurements of the miRNA abundances and relative miRNA qu...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491513/ https://www.ncbi.nlm.nih.gov/pubmed/31069233 http://dx.doi.org/10.3389/fmolb.2019.00017 |