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CD4+Foxp3+T Regulatory Cells Promote Transplantation Tolerance by Modulating Effector CD4+ T Cells in a Neuropilin-1-Dependent Manner

Several mechanisms of immune suppression have been attributed to Foxp3+ T regulatory cells (Treg) including modulation of target cells via inhibition of cell proliferation, alteration of cytokine secretion, and modification of cell phenotype, among others. Neuropilin-1 (Nrp1), a co-receptor protein...

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Detalles Bibliográficos
Autores principales: Campos-Mora, Mauricio, Contreras-Kallens, Pamina, Gálvez-Jirón, Felipe, Rojas, Masyelly, Rojas, Carolina, Refisch, Aarón, Cerda, Oscar, Pino-Lagos, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491519/
https://www.ncbi.nlm.nih.gov/pubmed/31068948
http://dx.doi.org/10.3389/fimmu.2019.00882