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Reduced caveolae density in arteries of SHR contributes to endothelial dysfunction and ROS production

Caveolae are plasma membrane invaginations enriched with high cholesterol and sphingolipid content; they also contain caveolin proteins in their structure. Endothelial nitric oxide synthase (eNOS), an enzyme that synthesizes nitric oxide (NO) by converting L-arginine to L-citrulline, is highly conce...

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Detalles Bibliográficos
Autores principales: Potje, Simone R., Grando, Marcella D., Chignalia, Andreia Z., Antoniali, Cristina, Bendhack, Lusiane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491560/
https://www.ncbi.nlm.nih.gov/pubmed/31040342
http://dx.doi.org/10.1038/s41598-019-43193-8