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Targeting mechanotransduction mechanisms and tissue weakening signals in the human amniotic membrane

Mechanical and inflammatory signals in the fetal membrane play an important role in extracellular matrix (ECM) remodelling in order to dictate the timing of birth. We developed a mechanical model that mimics repetitive stretching of the amniotic membrane (AM) isolated from regions over the placenta...

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Detalles Bibliográficos
Autores principales: Barrett, David W., John, Rebecca K., Thrasivoulou, Christopher, Mata, Alvaro, Deprest, Jan A., Becker, David L., David, Anna L., Chowdhury, Tina T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491562/
https://www.ncbi.nlm.nih.gov/pubmed/31040291
http://dx.doi.org/10.1038/s41598-019-42379-4