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Targeting mechanotransduction mechanisms and tissue weakening signals in the human amniotic membrane
Mechanical and inflammatory signals in the fetal membrane play an important role in extracellular matrix (ECM) remodelling in order to dictate the timing of birth. We developed a mechanical model that mimics repetitive stretching of the amniotic membrane (AM) isolated from regions over the placenta...
Autores principales: | Barrett, David W., John, Rebecca K., Thrasivoulou, Christopher, Mata, Alvaro, Deprest, Jan A., Becker, David L., David, Anna L., Chowdhury, Tina T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491562/ https://www.ncbi.nlm.nih.gov/pubmed/31040291 http://dx.doi.org/10.1038/s41598-019-42379-4 |
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