Temperature-dependent increase in the calcium sensitivity and acceleration of activation of ANO6 chloride channel variants

Anoctamin-6 (ANO6) belongs to a family of calcium (Ca(2+))-activated chloride channels (CaCCs), with three splicing variants (V1, V2, and V5) showing plasma membrane expression. Unlike other CaCCs, ANO6 requires a non-physiological intracellular free calcium concentration ([Ca(2+)](i) > 1 μM) and...

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Detalles Bibliográficos
Autores principales: Lin, Haiyue, Jun, Ikhyun, Woo, Joo Han, Lee, Min Goo, Kim, Sung Joon, Nam, Joo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491614/
https://www.ncbi.nlm.nih.gov/pubmed/31040335
http://dx.doi.org/10.1038/s41598-019-43162-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491614/
https://www.ncbi.nlm.nih.gov/pubmed/31040335
http://dx.doi.org/10.1038/s41598-019-43162-1

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