Cargando…

Increased Akt-Driven Glycolysis Is the Basis for the Higher Potency of CD137L-DCs

CD137 ligand-induced dendritic cells (CD137L-DCs) are a new type of dendritic cells (DCs) that induce strong cytotoxic T cell responses. Investigating the metabolic activity as a potential contributing factor for their potency, we find a significantly higher rate of glycolysis in CD137L-DCs than in...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, Qun, Mallilankaraman, Karthik, Schwarz, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491642/
https://www.ncbi.nlm.nih.gov/pubmed/31068941
http://dx.doi.org/10.3389/fimmu.2019.00868