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Increased Akt-Driven Glycolysis Is the Basis for the Higher Potency of CD137L-DCs
CD137 ligand-induced dendritic cells (CD137L-DCs) are a new type of dendritic cells (DCs) that induce strong cytotoxic T cell responses. Investigating the metabolic activity as a potential contributing factor for their potency, we find a significantly higher rate of glycolysis in CD137L-DCs than in...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491642/ https://www.ncbi.nlm.nih.gov/pubmed/31068941 http://dx.doi.org/10.3389/fimmu.2019.00868 |