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Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injury

BACKGROUND: Soluble amyloid-β oligomer (AβO) induced deleterious cascades have recently been considered to be the initiating pathologic agents of Alzheimer's disease (AD). However, little is known about the neurotoxicity and production of different AβOs. Understanding the production and spread...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Hou, Ting-ting, Jia, Long-fei, Wu, Qiao-qi, Quan, Mei-na, Jia, Jian-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491655/
https://www.ncbi.nlm.nih.gov/pubmed/30926423
http://dx.doi.org/10.1016/j.ebiom.2019.03.049