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Estimating parameters of nonlinear dynamic systems in pharmacology using chaos synchronization and grid search
Bridging fundamental approaches to model optimization for pharmacometricians, systems pharmacologists and statisticians is a critical issue. These fields rely primarily on Maximum Likelihood and Extended Least Squares metrics with iterative estimation of parameters. Our research combines adaptive ch...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491657/ https://www.ncbi.nlm.nih.gov/pubmed/30929120 http://dx.doi.org/10.1007/s10928-019-09629-4 |