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The Differentiation in vitro of Human Tonsil B Cells With the Phenotypic and Functional Characteristics of T-bet+ Atypical Memory B Cells in Malaria

Malaria is a deadly infectious disease associated with fundamental changes in the composition of the memory B cell (MBC) compartment, most notably a large expansion of T-bet(+) MBCs, termed atypical MBCs. However, we know little about the precursors of atypical MBCs and the conditions that drive the...

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Detalles Bibliográficos
Autores principales: Ambegaonkar, Abhijit A., Nagata, Satoshi, Pierce, Susan K., Sohn, Haewon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491666/
https://www.ncbi.nlm.nih.gov/pubmed/31068937
http://dx.doi.org/10.3389/fimmu.2019.00852