CD28 Individual Signaling Up-regulates Human IL-17A Expression by Promoting the Recruitment of RelA/NF-κB and STAT3 Transcription Factors on the Proximal Promoter

CD28 is an important co-stimulatory receptor for T lymphocytes that, in humans, delivers TCR-independent signal leading to the up-regulation of pro-inflammatory cytokines. We have recently reported that CD28 autonomous signaling induces the expression of IL-17A in peripheral CD4(+) T lymphocytes fro...

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Detalles Bibliográficos
Autores principales: Kunkl, Martina, Mastrogiovanni, Marta, Porciello, Nicla, Caristi, Silvana, Monteleone, Emanuele, Arcieri, Stefano, Tuosto, Loretta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491678/
https://www.ncbi.nlm.nih.gov/pubmed/31068940
http://dx.doi.org/10.3389/fimmu.2019.00864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491678/
https://www.ncbi.nlm.nih.gov/pubmed/31068940
http://dx.doi.org/10.3389/fimmu.2019.00864

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