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The Mechanical Stimulation of Myotubes Counteracts the Effects of Tumor-Derived Factors Through the Modulation of the Activin/Follistatin Ratio

Activin negatively affects muscle fibers and progenitor cells in aging (sarcopenia) and in chronic diseases characterized by severe muscle wasting (cachexia). High circulating activin levels predict poor survival in cancer patients. However, the relative impact of activin in mediating muscle atrophy...

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Detalles Bibliográficos
Autores principales: Baccam, Alexandra, Benoni-Sviercovich, Alexandra, Rocchi, Marco, Moresi, Viviana, Seelaender, Marilia, Li, Zhenlin, Adamo, Sergio, Xue, Zhigang, Coletti, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491697/
https://www.ncbi.nlm.nih.gov/pubmed/31068826
http://dx.doi.org/10.3389/fphys.2019.00401