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Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord

Following injury, the mammalian spinal cord forms a glial scar and fails to regenerate. In contrast, vertebrate fish spinal cord tissue regenerates significantly to restore function. Cord transection in zebrafish (Danio rerio) initially causes paralysis and neural cell death. Subsequently, ependymal...

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Detalles Bibliográficos
Autores principales: Nelson, Craig M., Lennon, Vanda A., Lee, Han, Krug, Randall G., Kamalova, Aichurok, Madigan, Nicolas N., Clark, Karl J., Windebank, Anthony J., Henley, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491705/
https://www.ncbi.nlm.nih.gov/pubmed/31069223
http://dx.doi.org/10.3389/fcell.2019.00056