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The Bone Marrow Edema Links to an Osteoclastic Environment and Precedes Synovitis During the Development of Collagen Induced Arthritis

Objectives: To determine the relationship between bone marrow edema (BME), synovitis, and bone erosion longitudinally using a collagen induced arthritis mice (CIA) model and to explore the potential pathogenic role of BME in bone erosion. Methods: CIA was induced in DBA/1J mice. BME and correspondin...

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Detalles Bibliográficos
Autores principales: Wang, Fang, Luo, Aishu, Xuan, Wenhua, Qi, Liang, Wu, Qing, Gan, Ke, Zhang, Qiande, Zhang, Miaojia, Tan, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491763/
https://www.ncbi.nlm.nih.gov/pubmed/31068949
http://dx.doi.org/10.3389/fimmu.2019.00884