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Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients

BACKGROUND: Autoimmune disease prevention requires tools to assess an individual's risk of developing a specific disease. One tool is disease-associated autoantibodies, which accumulate in an asymptomatic preclinical period. However, patients sometimes exhibit autoantibodies associated with a d...

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Detalles Bibliográficos
Autores principales: James, Judith A., Chen, Hua, Young, Kendra A., Bemis, Elizabeth A., Seifert, Jennifer, Bourn, Rebecka L., Deane, Kevin D., Demoruelle, M. Kristen, Feser, Marie, O'Dell, James R., Weisman, Michael H., Keating, Richard M., Gaffney, Patrick M., Kelly, Jennifer A., Langefeld, Carl D., Harley, John B., Robinson, William, Hafler, David A., O'Connor, Kevin C., Buckner, Jane, Guthridge, Joel M., Norris, Jill M., Holers, V. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491794/
https://www.ncbi.nlm.nih.gov/pubmed/30952617
http://dx.doi.org/10.1016/j.ebiom.2019.03.063