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Docosahexaenoic Acid Increases the Potency of Soluble Epoxide Hydrolase Inhibitor in Alleviating Streptozotocin-Induced Alzheimer’s Disease-Like Complications of Diabetes

Diabetes is a risk factor for Alzheimer’s disease and it is associated with significant memory loss. In the present study, we hypothesized that the soluble epoxide hydrolase (sEH) inhibitor N-[1-(1-oxopropyl)-4-piperidinyl]-N’-[4-(trifluoromethoxy)phenyl)-urea (also known as TPPU) could alleviate di...

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Detalles Bibliográficos
Autores principales: Pardeshi, Rohit, Bolshette, Nityanand, Gadhave, Kundlik, Arfeen, Mohammad, Ahmed, Sahabuddin, Jamwal, Rohitash, Hammock, Bruce D., Lahkar, Mangala, Goswami, Sumanta Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491817/
https://www.ncbi.nlm.nih.gov/pubmed/31068802
http://dx.doi.org/10.3389/fphar.2019.00288