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Non-linear Dose Response of Lymphocyte Cell Lines to Microtubule Inhibitors

Microtubule (MT) inhibitors show anti-cancer activity in a wide range of tumors in vitro and demonstrate high clinical efficacy. To date they are routinely included into many chemotherapeutic regimens. While the mechanisms of MT inhibitors’ interactions with tubulin have been well-established, the r...

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Detalles Bibliográficos
Autores principales: Potashnikova, Daria M., Saidova, Aleena A., Tvorogova, Anna V., Sheval, Eugene V., Vorobjev, Ivan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491834/
https://www.ncbi.nlm.nih.gov/pubmed/31068822
http://dx.doi.org/10.3389/fphar.2019.00436