Suppression of the RAC1/MLK3/p38 Signaling Pathway by β-Elemene Alleviates Sepsis-Associated Encephalopathy in Mice

It is still difficult to treat sepsis-associated encephalopathy (SAE) which is a diffuse brain dysfunction caused by sepsis, with excessive activation of microglia as one of the main mechanisms. Ras-related C3 botulinum toxin substrate 1 (RAC1) is proven to be a key molecule in the inflammatory sign...

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Detalles Bibliográficos
Autores principales: Pan, Cailong, Si, Yanna, Meng, Qinghai, Jing, Ling, Chen, Lu, Zhang, Yong, Bao, Hongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491839/
https://www.ncbi.nlm.nih.gov/pubmed/31068775
http://dx.doi.org/10.3389/fnins.2019.00358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491839/
https://www.ncbi.nlm.nih.gov/pubmed/31068775
http://dx.doi.org/10.3389/fnins.2019.00358

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