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Erythropoietin and Friedreich Ataxia: Time for a Reappraisal?

Friedreich ataxia (FRDA) is a rare neurological disorder due to deficiency of the mitochondrial protein frataxin. Frataxin deficiency results in impaired mitochondrial function and iron deposition in affected tissues. Erythropoietin (EPO) is a cytokine which was mostly known as a key regulator of er...

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Detalles Bibliográficos
Autores principales: Boesch, Sylvia, Indelicato, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491891/
https://www.ncbi.nlm.nih.gov/pubmed/31105516
http://dx.doi.org/10.3389/fnins.2019.00386