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Priming of HIV-1-specific CD8(+) T cells with strong functional properties from naïve T cells
BACKGROUND: HIV-1-specific CD8(+) T cells are required for immune suppression of HIV-1 replication and elimination of the associated viral reservoirs. However, effective induction of functional HIV-1-specific CD8(+) T cells from naïve cells remains problematic in the setting of human vaccine trials....
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491959/ https://www.ncbi.nlm.nih.gov/pubmed/30956171 http://dx.doi.org/10.1016/j.ebiom.2019.03.078 |