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Priming of HIV-1-specific CD8(+) T cells with strong functional properties from naïve T cells

BACKGROUND: HIV-1-specific CD8(+) T cells are required for immune suppression of HIV-1 replication and elimination of the associated viral reservoirs. However, effective induction of functional HIV-1-specific CD8(+) T cells from naïve cells remains problematic in the setting of human vaccine trials....

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Detalles Bibliográficos
Autores principales:	Kuse, Nozomi, Sun, Xiaoming, Akahoshi, Tomohiro, Lissina, Anna, Yamamoto, Takuya, Appay, Victor, Takiguchi, Masafumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491959/ https://www.ncbi.nlm.nih.gov/pubmed/30956171 http://dx.doi.org/10.1016/j.ebiom.2019.03.078

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