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Reduced cardiomyocyte Na(+) current in the age‐dependent murine Pgc‐1β (−/−) model of ventricular arrhythmia

Peroxisome proliferator‐activated receptor‐γ coactivator‐1 deficient (Pgc‐1β (−/−)) murine hearts model the increased, age‐dependent, ventricular arrhythmic risks attributed to clinical conditions associated with mitochondrial energetic dysfunction. These were accompanied by compromised action poten...

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Detalles Bibliográficos
Autores principales: Ahmad, Shiraz, Valli, Haseeb, Smyth, Robert, Jiang, Anita Y., Jeevaratnam, Kamalan, Matthews, Hugh R., Huang, Christopher L.‐H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492124/
https://www.ncbi.nlm.nih.gov/pubmed/30146680
http://dx.doi.org/10.1002/jcp.27183