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Genetic investigation of childhood vascular tumor biology reveals pathways for therapeutic intervention

Vascular tumors are neoplasms of endothelial cells, a significant number of which present in childhood. Recent studies have examined the mutational landscape of many subtypes of vascular tumors, identifying mutations primarily within the Ras–mitogen-activated protein kinase (MAPK) pathway and provid...

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Detalles Bibliográficos
Autores principales: Cheraghlou, Shayan, Lim, Young, Choate, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492225/
https://www.ncbi.nlm.nih.gov/pubmed/31069062
http://dx.doi.org/10.12688/f1000research.16160.1