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Low sulfated heparins target multiple proteins for central nervous system repair

The lack of endogenous repair following spinal cord injury (SCI) accounts for the frequent permanent deficits for which effective treatments are absent. Previously, we demonstrated that low sulfated modified heparin mimetics (LS‐mHeps) attenuate astrocytosis, suggesting they may represent a novel th...

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Detalles Bibliográficos
Autores principales: McCanney, George A., McGrath, Michael A., Otto, Thomas D., Burchmore, Richard, Yates, Edwin A., Bavington, Charles D., Willison, Hugh J., Turnbull, Jeremy E., Barnett, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492281/
https://www.ncbi.nlm.nih.gov/pubmed/30585359
http://dx.doi.org/10.1002/glia.23562