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Discovery and characterization of actionable tumor antigens

The nature of the tumor antigens that are detectable by T cells remains unclear. In melanoma, T cells were shown to react against major histocompatibility complex (MHC)-associated peptides (MAPs) that are derived from exonic mutations. A recent multi-omic study of hepatocellular carcinomas suggests,...

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Detalles Bibliográficos
Autores principales: Ehx, Grégory, Perreault, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492378/
https://www.ncbi.nlm.nih.gov/pubmed/31039809
http://dx.doi.org/10.1186/s13073-019-0642-x