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Joint analyses of multi-tissue Hi-C and eQTL data demonstrate close spatial proximity between eQTLs and their target genes

BACKGROUND: Gene regulation is important for cells and tissues to function. It has been studied from two aspects at the genomic level, the identification of expression quantitative trait loci (eQTLs) and identification of long-range chromatin interactions. It is important to understand their relatio...

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Detalles Bibliográficos
Autores principales: Yu, Jingting, Hu, Ming, Li, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492392/
https://www.ncbi.nlm.nih.gov/pubmed/31039743
http://dx.doi.org/10.1186/s12863-019-0744-x