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Hypoxia promotes colorectal cancer cell migration and invasion in a SIRT1-dependent manner
BACKGROUND: Hypoxic microenvironments play a significant role in the progression of colorectal cancer (CRC). Silencing information regulator 1 (SIRT1), a class III histone deacetylase, modulates the multiple biological behaviors of cancer. However, its role in CRC remains unclear. This study aims to...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492435/ https://www.ncbi.nlm.nih.gov/pubmed/31068761 http://dx.doi.org/10.1186/s12935-019-0819-9 |