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Hypoxia promotes colorectal cancer cell migration and invasion in a SIRT1-dependent manner

BACKGROUND: Hypoxic microenvironments play a significant role in the progression of colorectal cancer (CRC). Silencing information regulator 1 (SIRT1), a class III histone deacetylase, modulates the multiple biological behaviors of cancer. However, its role in CRC remains unclear. This study aims to...

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Detalles Bibliográficos
Autores principales:	Yu, Shentong, Zhou, Ru, Yang, Tong, Liu, Shuang, Cui, Zhuqing, Qiao, Qing, Zhang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492435/ https://www.ncbi.nlm.nih.gov/pubmed/31068761 http://dx.doi.org/10.1186/s12935-019-0819-9

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