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Emergence of the Dedifferentiated Phenotype in Hepatocyte‐Derived Tumors in Mice: Roles of Oncogene‐Induced Epigenetic Alterations

Hepatocellular carcinoma often reactivates the genes that are transiently expressed in fetal or neonatal livers. However, the mechanism of their activation has not been elucidated. To explore how oncogenic signaling pathways could be involved in the process, we examined the expression of fetal/neona...

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Detalles Bibliográficos
Autores principales: Watanabe, Kenji, Yamamoto, Masahiro, Xin, Bing, Ooshio, Takako, Goto, Masanori, Fujii, Kiyonaga, Liu, Yang, Okada, Yoko, Furukawa, Hiroyuki, Nishikawa, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492474/
https://www.ncbi.nlm.nih.gov/pubmed/31061957
http://dx.doi.org/10.1002/hep4.1327