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Emergence of the Dedifferentiated Phenotype in Hepatocyte‐Derived Tumors in Mice: Roles of Oncogene‐Induced Epigenetic Alterations
Hepatocellular carcinoma often reactivates the genes that are transiently expressed in fetal or neonatal livers. However, the mechanism of their activation has not been elucidated. To explore how oncogenic signaling pathways could be involved in the process, we examined the expression of fetal/neona...
Autores principales: | Watanabe, Kenji, Yamamoto, Masahiro, Xin, Bing, Ooshio, Takako, Goto, Masanori, Fujii, Kiyonaga, Liu, Yang, Okada, Yoko, Furukawa, Hiroyuki, Nishikawa, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492474/ https://www.ncbi.nlm.nih.gov/pubmed/31061957 http://dx.doi.org/10.1002/hep4.1327 |
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