Adipose‐Specific Lipin‐1 Overexpression Renders Hepatic Ferroptosis and Exacerbates Alcoholic Steatohepatitis in Mice

Lipin‐1 is a Mg(2+)‐dependent phosphatidic acid phosphohydrolase involved in the generation of diacylglycerol during synthesis of phospholipids and triglycerides. Ethanol‐mediated inhibitory effects on adipose‐specific lipin‐1 expression were associated with experimental steatohepatitis in rodents....

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Detalles Bibliográficos
Autores principales: Zhou, Zhou, Ye, Ting Jie, Bonavita, Gregory, Daniels, Michael, Kainrad, Noah, Jogasuria, Alvin, You, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492478/
https://www.ncbi.nlm.nih.gov/pubmed/31061954
http://dx.doi.org/10.1002/hep4.1333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492478/
https://www.ncbi.nlm.nih.gov/pubmed/31061954
http://dx.doi.org/10.1002/hep4.1333

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