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Adipose‐Specific Lipin‐1 Overexpression Renders Hepatic Ferroptosis and Exacerbates Alcoholic Steatohepatitis in Mice
Lipin‐1 is a Mg(2+)‐dependent phosphatidic acid phosphohydrolase involved in the generation of diacylglycerol during synthesis of phospholipids and triglycerides. Ethanol‐mediated inhibitory effects on adipose‐specific lipin‐1 expression were associated with experimental steatohepatitis in rodents....
Autores principales: | Zhou, Zhou, Ye, Ting Jie, Bonavita, Gregory, Daniels, Michael, Kainrad, Noah, Jogasuria, Alvin, You, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492478/ https://www.ncbi.nlm.nih.gov/pubmed/31061954 http://dx.doi.org/10.1002/hep4.1333 |
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