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Codelivery of DOX and siRNA by folate-biotin-quaternized starch nanoparticles for promoting synergistic suppression of human lung cancer cells

In this paper, the self-assembled folate-biotin-quaternized starch nanoparticles (FBqS NPs) were used as carrier system of doxorubicin (DOX) and siRNA(IGF1R) for the codelivery of both into human lung adenocarcinoma cell lines (A549 cells) in vitro. The cytotoxicity, targeted ligand competition, cel...

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Detalles Bibliográficos
Autores principales: Li, Liangping, He, Suoju, Yu, Lizhen, Elshazly, Ezzat H, Wang, Hui, Chen, Kuanmin, Zhang, Song, Ke, Lixia, Gong, Renmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493220/
https://www.ncbi.nlm.nih.gov/pubmed/31033359
http://dx.doi.org/10.1080/10717544.2019.1606363