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Quantification of 1D, a novel derivative of curcumin with potential antitumor activity, in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study in rats

Context: 1 D is a novel derivative of curcumin and shows very promising antitumor activities in various cancer cell lines. Objective: To characterize its preclinical pharmacokinetic profiles, a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the...

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Detalles Bibliográficos
Autores principales: Sun, Jialin, Jiang, Tao, Xu, Wen, Feng, Zhangying, Quan, Xianghua, Leng, Ping, Sun, Wei, Zhao, Jun, Jing, Fanbo, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493276/
https://www.ncbi.nlm.nih.gov/pubmed/31017510
http://dx.doi.org/10.1080/13880209.2019.1603243