The triacylglycerol, hydroxytriolein, inhibits triple negative mammary breast cancer cell proliferation through a mechanism dependent on dihydroceramide and Akt

The plasma membrane is an attractive target for new anticancer drugs, not least because regulating its lipid structure can control multiple signaling pathways involved in cancer cell proliferation, differentiation and survival. Accordingly, the novel anticancer drug hydroxytriolein (HTO) was designe...

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Detalles Bibliográficos
Autores principales: Guardiola-Serrano, Francisca, Beteta-Göbel, Roberto, Rodríguez-Lorca, Raquel, Ibarguren, Maitane, López, David J., Terés, Silvia, Alonso-Sande, María, Higuera, Mónica, Torres, Manuel, Busquets, Xavier, Escribá, Pablo V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493458/
https://www.ncbi.nlm.nih.gov/pubmed/31069012
http://dx.doi.org/10.18632/oncotarget.26824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493458/
https://www.ncbi.nlm.nih.gov/pubmed/31069012
http://dx.doi.org/10.18632/oncotarget.26824

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