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Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells

INTRODUCTION: Murine Kupffer cells (KCs) comprise CD11b(hi) and F4/80(hi) subsets. Tissue-resident macrophages are known to express the tyrosine kinase receptors colony-stimulating factor 1 receptor (Csf1r) and Mer. However, the expression of Csf1r and Mer on KC subsets and the importance of these t...

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Detalles Bibliográficos
Autores principales: Santamaria-Barria, Juan A., Zeng, Shan, Greer, Jonathan B., Beckman, Michael J., Seifert, Adrian M., Cohen, Noah A., Zhang, Jennifer Q., Crawley, Megan H., Green, Benjamin L., Loo, Jennifer K., Maltbaek, Joanna H., DeMatteo, Ronald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493758/
https://www.ncbi.nlm.nih.gov/pubmed/31042769
http://dx.doi.org/10.1371/journal.pone.0216275