Cargando…
Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells
INTRODUCTION: Murine Kupffer cells (KCs) comprise CD11b(hi) and F4/80(hi) subsets. Tissue-resident macrophages are known to express the tyrosine kinase receptors colony-stimulating factor 1 receptor (Csf1r) and Mer. However, the expression of Csf1r and Mer on KC subsets and the importance of these t...
Autores principales: | Santamaria-Barria, Juan A., Zeng, Shan, Greer, Jonathan B., Beckman, Michael J., Seifert, Adrian M., Cohen, Noah A., Zhang, Jennifer Q., Crawley, Megan H., Green, Benjamin L., Loo, Jennifer K., Maltbaek, Joanna H., DeMatteo, Ronald P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493758/ https://www.ncbi.nlm.nih.gov/pubmed/31042769 http://dx.doi.org/10.1371/journal.pone.0216275 |
Ejemplares similares
-
The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor
por: Zhang, Jennifer Q., et al.
Publicado: (2020) -
Oncogenic kinase inhibition limits Batf3-dependent dendritic cell development and antitumor immunity
por: Medina, Benjamin D., et al.
Publicado: (2019) -
The Role of IL-1 Family Members and Kupffer Cells in Liver Regeneration
por: Tan, Quanhui, et al.
Publicado: (2016) -
Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation
por: Sorenson, Eric C., et al.
Publicado: (2017) -
Kupffer cells in hepatotoxicity
por: Hassan, Reham
Publicado: (2020)