Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria

Staphylococcus aureus and other bacterial pathogens affix wall teichoic acids (WTAs) to their surface. These highly abundant anionic glycopolymers have critical functions in bacterial physiology and their susceptibility to β-lactam antibiotics. The membrane-associated TagA glycosyltransferase (GT) c...

Descripción completa

Detalles Bibliográficos
Autores principales: Kattke, Michele D., Gosschalk, Jason E., Martinez, Orlando E., Kumar, Garima, Gale, Robert T., Cascio, Duilio, Sawaya, Michael R., Philips, Martin, Brown, Eric D., Clubb, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493773/
https://www.ncbi.nlm.nih.gov/pubmed/31002736
http://dx.doi.org/10.1371/journal.ppat.1007723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493773/
https://www.ncbi.nlm.nih.gov/pubmed/31002736
http://dx.doi.org/10.1371/journal.ppat.1007723

Ejemplares similares