Somatic mutations render human exome and pathogen DNA more similar

Immunotherapy has recently shown important clinical successes in a substantial number of oncology indications. Additionally, the tumor somatic mutation load has been shown to associate with response to these therapeutic agents, and specific mutational signatures are hypothesized to improve this asso...

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Detalles Bibliográficos
Autores principales: Ebrahimzadeh, Ehsan, Engler, Maggie, Tse, David, Cristescu, Razvan, Tchamkerten, Aslan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494387/
https://www.ncbi.nlm.nih.gov/pubmed/31042711
http://dx.doi.org/10.1371/journal.pone.0197949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494387/
https://www.ncbi.nlm.nih.gov/pubmed/31042711
http://dx.doi.org/10.1371/journal.pone.0197949

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