Cargando…

HDAC Regulates Transcription at the Outset of Axolotl Tail Regeneration

Tissue regeneration is associated with complex changes in gene expression and post-translational modifications of proteins, including transcription factors and histones that comprise chromatin. We tested 172 compounds designed to target epigenetic mechanisms in an axolotl (Ambystoma mexicanum) embry...

Descripción completa

Detalles Bibliográficos
Autores principales: Voss, S. Randal, Ponomareva, Larissa V., Dwaraka, Varun B., Pardue, Kaitlin E., Baddar, Nour W. Al Haj, Rodgers, A. Katherine, Woodcock, M. Ryan, Qiu, Qingchao, Crowner, Anne, Blichmann, Dana, Khatri, Shivam, Thorson, Jon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494824/
https://www.ncbi.nlm.nih.gov/pubmed/31043677
http://dx.doi.org/10.1038/s41598-019-43230-6