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Beta1 integrin blockade overcomes doxorubicin resistance in human T-cell acute lymphoblastic leukemia
Growing evidence indicates that cell adhesion to extracellular matrix (ECM) plays an important role in cancer chemoresistance. Leukemic T cells express several adhesion receptors of the β1 integrin subfamily with which they interact with ECM. However, the role of β1 integrins in chemoresistance of T...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494825/ https://www.ncbi.nlm.nih.gov/pubmed/31043590 http://dx.doi.org/10.1038/s41419-019-1593-2 |