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Beta1 integrin blockade overcomes doxorubicin resistance in human T-cell acute lymphoblastic leukemia

Growing evidence indicates that cell adhesion to extracellular matrix (ECM) plays an important role in cancer chemoresistance. Leukemic T cells express several adhesion receptors of the β1 integrin subfamily with which they interact with ECM. However, the role of β1 integrins in chemoresistance of T...

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Detalles Bibliográficos
Autores principales: Berrazouane, Sofiane, Boisvert, Marc, Salti, Suzanne, Mourad, Walid, Al-Daccak, Reem, Barabé, Frédéric, Aoudjit, Fawzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494825/
https://www.ncbi.nlm.nih.gov/pubmed/31043590
http://dx.doi.org/10.1038/s41419-019-1593-2

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