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PRMT1 regulates the tumour-initiating properties of esophageal squamous cell carcinoma through histone H4 arginine methylation coupled with transcriptional activation

Esophageal squamous cell carcinoma (ESCC) is the most difficult subtype of esophageal cancer to treat due to a paucity of effective targeted therapy. ESCC is believed to arise from tumour initiating cells (TICs), which contribute to metastasis and chemoresistance. In this study, we found that Protei...

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Detalles Bibliográficos
Autores principales: Zhao, Yue, Lu, Qijue, Li, Chunguang, Wang, Xinyu, Jiang, Long, Huang, Lei, Wang, Chao, Chen, Hezhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494844/
https://www.ncbi.nlm.nih.gov/pubmed/31043582
http://dx.doi.org/10.1038/s41419-019-1595-0