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Synthesis and in vivo characterization of (18)F-labeled difluoroboron-curcumin derivative for β-amyloid plaque imaging
Positron emission tomography imaging of β-amyloid (Aβ) plaques has proven useful in the diagnosis of Alzheimer’s disease. A previous study from our group showed that 4′-O-[(18)F]fluoropropylcurcumin has poor brain permeability, which is thought to be due to its rapid metabolism. In this study, we sy...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494845/ https://www.ncbi.nlm.nih.gov/pubmed/31043696 http://dx.doi.org/10.1038/s41598-019-43257-9 |