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Synthesis and in vivo characterization of (18)F-labeled difluoroboron-curcumin derivative for β-amyloid plaque imaging

Positron emission tomography imaging of β-amyloid (Aβ) plaques has proven useful in the diagnosis of Alzheimer’s disease. A previous study from our group showed that 4′-O-[(18)F]fluoropropylcurcumin has poor brain permeability, which is thought to be due to its rapid metabolism. In this study, we sy...

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Detalles Bibliográficos
Autores principales:	Kim, Hyunjung, Im, Young Hoon, Ahn, Jinhee, Yang, Jehoon, Choi, Joon Young, Lee, Kyung-Han, Kim, Byung-Tae, Choe, Yearn Seong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494845/ https://www.ncbi.nlm.nih.gov/pubmed/31043696 http://dx.doi.org/10.1038/s41598-019-43257-9

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