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The Rabl configuration limits topological entanglement of chromosomes in budding yeast

The three dimensional organization of genomes remains mostly unknown due to their high degree of condensation. Biophysical studies predict that condensation promotes the topological entanglement of chromatin fibers and the inhibition of function. How organisms balance between functionally active gen...

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Detalles Bibliográficos
Autores principales: Pouokam, Maxime, Cruz, Brian, Burgess, Sean, Segal, Mark R., Vazquez, Mariel, Arsuaga, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494875/
https://www.ncbi.nlm.nih.gov/pubmed/31043625
http://dx.doi.org/10.1038/s41598-019-42967-4