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The Rabl configuration limits topological entanglement of chromosomes in budding yeast
The three dimensional organization of genomes remains mostly unknown due to their high degree of condensation. Biophysical studies predict that condensation promotes the topological entanglement of chromatin fibers and the inhibition of function. How organisms balance between functionally active gen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494875/ https://www.ncbi.nlm.nih.gov/pubmed/31043625 http://dx.doi.org/10.1038/s41598-019-42967-4 |